Oriental Journal of Biology and Chemistry

DETERIORATING AIR QUALITY IN LARGE CITIES AND AN INCREASE IN CARDIOVASCULAR DISEASES

Farida Azizova — 2025-04-24

This article analyzes the relationship between poor air quality in large cities and an increase in cardiovascular disease. The link between air pollution and cardiovascular health has been proven by numerous scientific studies, and this problem affects not only physical but also mental health. Studies show that air pollution leads to an increase in cardiovascular diseases, such as high blood pressure, stroke and heart attack, in large cities. The article examines the main factors of air pollution, including industrial emissions, road traffic and construction work, and also highlights effective measures to reduce the negative effects of this problem, such as strengthening environmental policies, expanding green areas and increasing the environmental literacy of the population. The article shows the importance of improving urban ecology and public health.

ENVIRONMENTAL POLLUTION AS A RISK FACTOR FOR MYOCARDIAL PATHOMORPHOLOGY

Farida Azizova — 2025-09-30

This article examines the impact of long-term environmental stress on the morphological state of the myocardium. The presented data indicate the development of structural changes in cardiac muscle tissue under the influence of environmental pollutants such as particulate matter, nitrogen oxides, heavy metals, and toxic compounds. Special attention is given to pathomorphological changes — myolysis, interstitial fibrosis, mitochondrial disorders, and epigenetic alterations. The importance of early diagnosis and preventive strategies is emphasized in the context of a deteriorating environmental situation.

MSCT ANGIOGRAPHY IN PATIENTS WITH ISCHEMIC STROKE WITHIN THE THERAPEUTIC WINDOW

M.M. Baxadirkhanov — 2025-08-30

Ischemic stroke is a leading cause of death and disability worldwide, requiring rapid diagnosis and immediate therapy. Multislice computed tomography angiography (MSCTA) is a highly informative, non-invasive diagnostic tool that visualizes cerebral vessels, detects thrombosis and stenosis, and assesses collateral circulation. This article reviews the diagnostic value of MSCTA within the therapeutic window for ischemic stroke, its impact on treatment strategies, and long-term patient prognosis. The capabilities and limitations of the method, as well as prospects for technological advancements, are discussed.

ASSESSMENT OF COGNITIVE AND NEUROPSYCHOLOGICAL DISORDERS IN URBAN SETTINGS DURING TRANSIENT ISCHEMIC ATTACKS

Muso Boltaevich Urinov — 2025-09-12

Transient ischemic attacks (TIA) are short-term but significant episodes of cerebral blood circulation disorders that are considered a precursor to the development of ischemic stroke. Despite the rapid recovery of neurological functions, a large proportion of patients who experience TIA retain cognitive and neuropsychological impairments. These impairments affect quality of life, work capacity, and increase the risk of recurrent vascular events (1,2).