FEATURES OF THE DYNAMICS OF CLINICAL, NEUROLOGICAL AND NEUROPHYSIOLOGICAL MANIFESTATIONS OF POLYNEUROPATHY OF CORONAVIRUS ETIOLOGY

Section: Articles Published Date: 2024-05-18 Pages: 1-7 Views: 0 Downloads: 0

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Abstract

The high incidence of the new coronavirus infection COVID-19, the diversity of organs and body systems involved in the pathological process of this disease, and the often severe course with disabling consequences have aroused deep interest in this problem. Frequent damage to the peripheral nervous system (PNS) has been established in patients with COVID-19, which has led to the assumption that the SARS-CoV-2 coronavirus is neurotropic. The article presents information about PNS lesions in COVID-19 and discusses possible mechanisms of their development. Among others, it has been suggested that immune disorders play a key role in the initiation and subsequent progression of changes in the PNS. Information is provided on the possible role of metabolic disorders of B vitamins in the pathogenesis of PNS lesions in COVID-19, including through the influence on various parts of the immune system, and on the connection between B vitamin deficiency and a more severe course of the disease.

Keywords

PNS, autoimmune damage, COVID-19, polyneuropathy.