MICRO- AND MACRO-VASCULAR DISORDERS IN OBESE PREGNANT WOMEN

Abstract

Obesity during pregnancy is a significant risk factor for both microvascular and macrovascular complications, which can adversely affect maternal and fetal outcomes. This review examines the pathophysiological mechanisms underlying these vascular disorders in obese pregnant women, highlighting the role of insulin resistance, inflammation, and endothelial dysfunction. Microvascular complications, including gestational hypertension and preeclampsia, are discussed alongside macrovascular conditions such as coronary artery disease and stroke. The interplay between these vascular complications and pregnancy-specific changes is explored to provide a comprehensive understanding of the heightened risks faced by obese pregnant women. Strategies for monitoring, prevention, and management are also addressed, emphasizing the importance of early detection and intervention to improve health outcomes for both mother and child.

Keywords

Obesity, Pregnancy, Microvascular complications, Macrovascular disorders, Gestational hypertension, Preeclampsia, Coronary artery disease, Stroke, Insulin resistance, Inflammation, Endothelial dysfunction, Maternal health, Fetal outcomes, Vascular health.