THE IMPORTANCE OF ANTIBIOTIC RESISTANCE IN MEDICAL PRACTICE AND THE RELEVANCE OF ITS PREVENTION

Section: Articles Published Date: 2025-12-18 Pages: 98-109 Views: 0 Downloads: 0

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Abstract

A thorough understanding of the emergence, processes, advancements, and implications of antimicrobial resistance (AMR), which is often seen as a major worldwide public health problem, is necessary.  The epidemiological landscape of antimicrobial resistance (AMR) is marked by its extensive prevalence and ever-changing patterns, with multidrug-resistant organisms (MDROs) posing new problems on a daily basis.  The establishment and spread of novel resistance strains are facilitated by the most prevalent processes driving AMR, which include genetic alterations, horizontal gene transfer, and selective pressure. Antimicrobial stewardship programs (ASPs) and infection prevention and control strategies (IPCs) are examples of mitigation techniques that highlight the significance of responsible antimicrobial use and surveillance. The interdependence of human, animal, and environmental health is highlighted by a One Health approach, which emphasizes the need for interdisciplinary cooperation and all-encompassing tactics in the fight against AMR.  Novel treatment developments (such as vaccines and other antimicrobial medicines) present intriguing ways to address AMR issues.  ASPs that seek to control the use of antibiotics are also supported by national and international policy measures.  Even with all of the progress that has been seen, antimicrobial resistance (AMR) is still a serious issue that requires ongoing work to address new threats and advance the sustainability of antibiotics.  Future studies must focus on novel strategies and tackle the intricate socioecological factors that underlie AMR.  For researchers, legislators, and medical professionals trying to understand the complicated AMR landscape and create practical mitigation methods, this book is an extensive resource.

Keywords

Antimicrobial resistance, antibiotic stewardship initiatives, epidemiology, mechanisms, innovative treatments, the One Health concept, policy interventions.