PREDICTORS OF SEVERE SYSTEMIC LUPUS ERYTHEMATOSUS
K. R. Abdushukurova , Samarkand State Medical University Samarkand, Uzbekistan N. Sh. Toshnazarova , Samarkand State Medical University Samarkand, Uzbekistan Sh. X. Ziyadullayev , Samarkand State Medical University Samarkand, UzbekistanAbstract
The aim of the study was to assess the nature of lesions and to identify risk factors of lesions in our group of patients with SLE. A retrospective review of charts and case histories in the Internal Medicine Department of the SamMU’s clinic was carried out on a group of 75 patients with SLE. 225 people were included in this study: 75 in the main group (cases) and 150 in the control group (healthy controls). The results show that the presence of neuropsychiatric manifestations is a significant risk factor for lesions. Other likely risk factors for lesions include younger age at diagnosis, more major organ damage, more exacerbations and serious infections.
Keywords
SLE, risk factors, retrospective, case-control study
References
Ravshanova MS, Ibragimov KI. COMMON RISK FACTORS FOR ECTOPIC PREGNANCY IN YOUNG ADULTS: CLINIC-BASED CASE CONTROL STUDY. InINTERNATIONAL SCIENTIFIC CONFERENCE" INNOVATIVE TRENDS IN SCIENCE, PRACTICE AND EDUCATION" 2022 Sep 10 (Vol. 1, No. 2, pp. 106-107).
Li, Xinrui, et al. Fcγ receptors: structure, function and role as genetic risk factors in SLE.// Genes & Immunity (2019). 10 (5). p.380-389.
Petri, M., and M. Genovese. Incidence of and risk factors for hospitalizations in systemic lupus erythematosus: a prospective study of the Hopkins Lupus Cohort." The //Journal of rheumatology (2012). 19(10). p.1559-1565.
Ibragimov K, Keane G, Glaría CC, Cheng J, Llosa A. Haloperidol versus olanzapine for people with schizophrenia. The Cochrane Database of Systematic Reviews. 2019 Oct;2019(10).
Jara, Luis J., et al. Risk factors of systemic lupus erythematosus flares during pregnancy.// Immunologic research (2014). 60. p.184-192.
Angelica Sinicato N, et al.. Risk factors in cardiovascular disease in systemic lupus erythematosus.// Current Cardiology Reviews. (2013). 9(1). p.15-9.
Kh I, Sultonov I, Islamova K, Axmedov I, Baysariyev S. The Risk of Cardiovascular Disease in Patients with Rheumatoid Arthritis Treated with Conventional DMARDs: a Clinic Based Case Control Study.
Gergianaki I, et al. Update on the epidemiology, risk factors, and disease outcomes of systemic lupus erythematosus.// Best Practice & Research Clinical Rheumatology. (2018).32(2). p.188-205.
Иргашева У. З., Тоиров Э. С., Ахмедов И. А. Электрокардиографические изменения у больных артериальной гипертонией женщин пери и постменопаузального возраста //Академический журнал Западной Сибири. – 2012. – №. 1. – С. 10-10.
Yang H, et al. Pregnancy-related systemic lupus erythematosus: clinical features, outcome and risk factors of disease flares-a case-control study.// PloS one. (2014).9(8).e104375.
Ишанкулова Н. Н. и др. Оценка качества ведения пациентов с артериальной гипертонией в условиях семейной поликлиники //Здоровье, демография, экология финно-угорских народов. – 2019. – №. 4. – С. 29-31.
Sayarlioglu M, et al. Risk factors for avascular bone necrosis in patients with systemic lupus erythematosus. //Rheumatology international. (2012). 32. p.177-82.
Ишанкулова Н. Н., Абдашукурова К. Р., Ахмедов И. А. ЛХ Ташинова Оценка качества ведения пациентов с артериальной гипертензией в условиях семейной поликлиники //здоровье демография экология финно-угорских народов. – 2019. – №. 1.
Article Statistics
Copyright License
Copyright (c) 2023 K. R. Abdushukurova , N. Sh. Toshnazarova, Sh. X. Ziyadullayev
This work is licensed under a Creative Commons Attribution 4.0 International License.