to study the state of intestinal microbiocenosis in diarrhea in HIV-infected children.

During the study, 876 children under the age of 18 were examined. Healthy children - 130 people, group 1 - 261 children with HIV infection with diarrhea, group 2 - 247 children with only diarrhea without HIV infection and group 3 - 238 children with HIV infection without diarrhea.

In HIV-infected children with acute diarrhea, there was a sharp decrease in obligate (Bacteroides spp., Bifidobacterium spp., Lactobacillus spp., E. coli lac+) and an increase in facultative intestinal microflora (E. coli lac-, Enterobacter spp., Enterococcus spp. ., Staphylococcus spp.). High values of Candida spp., Salmonella, Shigella, Cambilobacter, Yersinia were also recorded (P>0.05). This probably indicates the development of invasive diarrhea. High dysbiotic changes in acute infectious diarrhea in HIV-positive children require the introduction of drugs that restore intestinal microbiocenosis into their treatment regimen.

HIV infection, children, intestinal microbiocenosis

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