STUDY OF ACUTE TOXICITY AND PSYCHOPHARMACOLOGICAL ACTIVITY OF 1-(2-HYDROXYPHENYL)-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE

Section: Articles Published Date: 2022-06-02 Pages: 65-71 Views: 13 Downloads: 21

Authors

  • Zafar I. Sanoev Researcher Institute of Chemistry and Plant Substances Academy of Sciences RUz Tashkent, Uzbekistan
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Abstract

The acute toxicity and psychopharmacological activity of 1-(2-hydroxyphenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline at doses from 1 to 100 mg/kg was studied. In doses of 10 and 20 mg/kg, intragastric administration revealed sedative-anxiolytic properties.

Keywords

1-(2-hydroxyphenyl)-6, 7-dimethoxy-1,2,3,4-tetrahydroisoquinoline,, acute toxicity