STUDY OF N-DEACETYLAPPACONITINE (N-DAL) ANTICONVULSANT ACTION
Abstract
In this article, we studied an anticonvulsant model induced by different analyzers of corazole (80 mg/kg s.c.), strychnine (1.2 mg/kg s.c.), isoniazid (300 mg/kg ip) and bicuculin (2.7 mg/kg s.c.) when administered orally to white mice, N-deacetylappaconitin at doses of 0.01; 0.05; 0.1; 0.5; 1.0 and 2.0 mg/kg anticonvulsant effect of the test substance, comparative drug carbamazepine and control groups. The anticonvulsant effect of N-deacetylappaconitine, carbamazepine and the control group at various doses was studied and the necessary conclusions were drawn.
Keywords
N-deacetylappaconitine, convulsions, corazoleHow to Cite
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